Coenzyme Q10 can restore quality of life in patients with chronic heart failure.
Several published studies show that patients with chronic heart failure (CHF) benefit from taking supplements of the vitamin-like compound coenzyme Q10. The treatment enables their heart muscle to contract with greater force, their exercise tolerance increases, and they can generally enjoy life in a different way because they are less likely to feel the limitations of their condition.
CHF patients are normally categorized according to the New York Heart Association (NYHA) Functional Classification (see below), which places patients in one of four groups based on how limited they are during physical activity (in terms of breathing, shortness of breath, chest pain etc.
There are documented examples of CHF patients who have improved 1-2 NYHA classes as a result of receiving coenzyme Q10 supplementation in the range of 100-300 mg/day.
NYHA Class Symptom description
I No symptoms and no limitations in ordinary physical activity, e.g. shortness of breath when walking, climbing stairs, etc.
II Mild symptoms (mild shortness of breath and/or angina) and slight limitation during ordinary activity
II Marked limitation in activity due to symptoms, even during less-than-ordinary activity, e.g. walking short distances (20-100 meters). Comfortable only at rest.
IV Severe limitations. Experience symptoms even while at rest. Mostly bed-bound patients.
(Reference: The Criteria Committee of the New York Heart Association. Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels. 9th ed. Boston, Mass: Little, Brown & Co; 1994:253-256.)