It is well established that coronary artery disease (CAD) is associated with inflammatory processes and coenzyme Q10 may hold a promising role in reducing this inflammation by way of different mechanisms. A group of Taiwanese researchers from Chung Shan Medical University and the Intensive Care Unit of Taichung Veterans General found in a recent study that the nutrient successfully lowered levels of the inflammatory marker IL-6 (interleukin-6) in patients who were given a daily dose of 150 mg coenzyme Q10 for 12 weeks.
The study was conducted on 40 patients with coronary artery disease who were randomly assigned to three groups: a placebo group, a 60 mg/day coenzyme Q10 group, or a 150 mg/day coenzyme Q10 group. All groups followed the prescribed intervention for 12 weeks. Levels of inflammatory markers, including IL-6, C-reactive Protein, and homocysteine, plus superoxide dismutase (an endogenous antioxidant enzyme) were measured before and after.
Subjects in the 150 mg coenzyme Q10 group had significantly lower levels of IL-6 and malondialdehyde (a marker of lipid peroxidation). At the same time, subjects in both Q10 groups had increased superoxide dismutase activity, which is a sign of improved antioxidant protection.
On behalf of these findings, the researchers conclude that coenzyme Q10 taken at a dosage of 150 mg/day appears to decrease the inflammatory marker IL-6 in patients with coronary artery disease.
Source: Nutrition. 2012 Feb 16.
Is CoQ10 good for erectile disfunction?
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Excellent, Dr Lee,
you have provided a proof.
Kumar et al, Acta Cardiol 2007; 62:349-54. Effects of carniqgel on cytokines in patients with heart failure.
Singh et al, Acta Cardiologica 2014;69:391-98. Inflammatory mediators of chronic heart failure in North India.
We observed it 2005 during QSymbio trial but later conducted above trial.
RBSingh
Good evening. My question is not on heart disease but fibromyalgia. Is there any reliable, published, scientific study on the use of CoQ10 to treat fibromyalgia, that is, to relieve symptoms of muscle pain and fatigue? Thank you.
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HI… i’m In the middle of thesis…. is there any journal
About topical Coq10 for reduce mmp1? Thanks
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