The International CoQ10 Association and Antioxidants journal has agreed to publish a special issue titled The Ubiquitous and Multifaceted Coenzyme Q, which will cover the new discoveries and research perspectives on CoQ and its role in health and diseases, and its importance in cellular redox homeostasis. A particular focus will be on studies on its biosynthesis and regulation. We invite all participants of the 10th International Scientific Meeting (Hamburg, May 12-15, 2022) to contribute to this special issue with original articles and reviews based on their recent results or expertise presented in the meeting.